Qualifications

Experience in large-scale genetics studies involving physicians and scientists from different areas

  • Leading/led the analysis in the following studies
    • Endometrial cancer project, samples from 96 patients
    • Genome-wide Mutation Landscape in POLEP286R Engineered Mice
    • Kidney Cancer Pprojects, 697 tumor and normal samples from 219 patients
    • PUUMA MI and plasma lipid association study, 10030 samples from China
    • HUNT MI and plasma lipid association study, 6000 samples from Norway
  • Paticipate in the following studies
    • NHLBI Exome sequencing project (ESP), 5500 samples
    • GLGC meta-analysis of plasma lipid association study, >300000 samples

Experience in management, analysis and interpretation of large-scale genomics/genetics data

  • DNA sequencing (Whole genome sequencing, whole exome sequencing, target sequencing)
  • Exome sequencing
  • RNA sequencing
  • Ribosome profiling (ribo-seq)
  • Microarray: Agilent SNP array, Illumina exome chip, etc

Experience in developing bioinformatics pipelines, methods and databases

  • Development of a new method to identify somatic copy number alterations (DEFOR)
  • Development of pipeline for next generation sequencing data
  • Development of PlantTFDB

Progamming

  • Proficient in linux; Linux server management (Ubuntu, ArchLinux and Gentoo)
  • Programing using C, Perl, Python and Bash
  • Designing and implementing statistical models using R
  • Database management using MySQL and SQLite
  • Web development using PHP, HTML and JavaScript